The theory is said to have been definitively refuted by Louis Pasteur, who also suggested that "life only derives from life."
The concept of "spontaneous generation" held that life things can emerge from non-living things. Louis Pasteur notably devised an experiment that refuted the hypothesis in a debate between biologist Felix Pouchet and chemist Louis Pasteur staged by the French Academy of Sciences in the late 19th century. The earliest observations of bacteria and protozoa were made by Antonie van Leeuwenhoek using single-lens microscopes that he created. His in-depth study of the development of tiny creatures like fleas, mussels, and eels contributed to the debunking of the hypothesis of life's spontaneous creation.
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