The main energetic driving force for the formation of phospholipid bilayers is hydrophobic interactions.
The main energetic factor behind the synthesis of lipid bilayers is hydrophobic interactions between the hydrocarbon tails. Phospholipid molecules, which are cylindrical, naturally form bilayers in water settings.
The hydrophilic heads face the water at each bilayer surface in this energetically most-favourable configuration, while the hydrophobic tails are rescued from the water inside.
Self-healing is a function of the same mechanisms that cause phospholipids to form bilayers. An energetically unfavourable tiny tear in the bilayer results in a free edge with water; as a result, the lipids spontaneously rearrange to close the gap.
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