When ketone bodies are present in the blood and urine in large amounts, it usually indicates increased metabolism of fat.
The ketone groups produced by the liver from fatty acids are included in ketone bodies, which are water-soluble molecules. The conversion of ketone bodies into acetyl-CoA, which enters the citric acid cycle and is used for energy, occurs in tissues beyond the liver.
When there is a shortage of glucose, such as during prolonged fasting, intense activity, or pathological diseases like diabetes, ketone bodies act as the brain's primary fuel source.
Your body produces ketones when your cells don't receive enough glucose (blood sugar). Your body uses glucose as its primary energy source. Ketones can be detected in the urine or blood.
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