A patient who takes pancreatic enzyme replacements is at risk of diarrhea, constipation, abdominal pain, cramps, bloating, nausea, or vomiting types of gastrointestinal side effects.
Pancreatic enzyme replacement therapy is a method of treating pancreatic exocrine insufficiency. There are many causes of pancreatic exocrine insufficiency such as chronic pancreatitis, cystic fibrosis and pancreatic cancer.
Pancreatic exocrine insufficiency is the deficiency of the pancreatic enzymes within the lumen, which result in the intestinal malabsorption.
Pancreatic exocrine insufficiency also causes several different types of diseases which share a common pathophysiological end result of inadequate enzyme digestion.
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