A patient with gastroesophageal reflux disease (gerd) is to begin taking oral metoclopramide [reglan]. the patient asks the nurse about the medication. which response by the nurse is correct?

Respuesta :

A patient with gastroesophageal reflux disease (GERD) is to begin taking oral metoclopramide [reglan] the patient is advised by the nurse to take the medicines 30mins before each meal &amp bedtime.

Metoclopramide should not be used for an extended period of time, and increasing the dose after three months is not advised.

  • Metoclopramide is a medication used to treat hiccups; it does not produce them.
  • Tardive dyskinesia is a severe and permanent adverse effect.

What is the mechanism of action of metoclopramide?

Metoclopramide works as an antiemetic by blocking dopamine D2 and serotonin 5-HT3 receptors in the chemoreceptor trigger zone (CTZ), which is located in the brain's postrema region.

  • This medication causes prokinetic effects via inhibiting presynaptic and postsynaptic D2 receptors, agonism of serotonin 5-HT4 receptors, and antagonism of muscarinic receptor inhibition.
  • This effect increases acetylcholine release, resulting in enhanced lower oesophagal sphincter (LES) and gastric tone, hence expediting gastric emptying and transit into the gut.
  • Metoclopramide inhibits dopamine D2 receptors.

Learn more about metoclopramide here,

https://brainly.com/question/3197821

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