The zone of polarizing activity that scandalizes the limb bud expresses the morphogen SHH.
What is morphogen?
- A morphogen is a substance whose uneven distribution controls the pattern of tissue development during the process of morphogenesis, also known as pattern formation.
- Pattern formation is one of the central stages in developmental biology and determines the locations of different specialized cell types within a tissue.
- Signaling molecules known as morphogens function over long distances to cause reactions in cells depending on the concentration of morphogen that the cells are exposed.
- Morphogens are chemicals that are hypothesized to be important for cell patterning during embryonic development.
- A chemical whose diffusional dispersion might control the growth of cells that would react differently to varied morphogen concentrations.
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