Globulins is a plasma protein that serves as a defense mechanism of the immune system.
The globulins are a class of globular proteins that are insoluble in pure water but dissolve in diluted salt solutions. They have greater molecular weights than albumins. While the immune system produces some globulins, the liver produces others. The three main blood proteins are fibrinogen, albumins, and globulins. About 2.6 to 3.5 g/dL of globulins are typically present in human blood.
Sometimes "globulin" and "globular protein" are used interchangeably. Albumins are globular proteins as well, but they are not globulins. Globulins are the only other serum globular proteins.
Serum protein electrophoresis can be used to separate globulins from one another.
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