Because of the absence of endonuerium, damaged nerve fibers in the cns cannot regenerate.
What is endoneurium?
- The peripheral nervous system's endoneurium, also known as the endoneurial channel, endoneurial sheath, endoneurial tube, or Henle's sheath, is a thin layer of connective tissue that surrounds each myelinated nerve fiber's myelin sheath.
- Endoneurial cells are its constituent cells.
- The endoneuria are organized into groups termed nerve fascicles with their encased nerve fibers, with each fascicle contained within its own protective sheath known as a perineurium.
- Multiple fascicles, each with its own blood supply and fatty tissue, may be wrapped within yet another sheath, the epineurium, in sufficiently large nerves. A little-protein-containing fluid called endoneurial fluid is found inside the endoneurium.
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