The ratio of the toxic dose of an antimicrobial drug (that is toxic to humans) to its minimum therapeutic dose is the therapeutic index.
What are antimicrobials?
Antibiotics, antivirals, antifungals, and antiparasitics are examples of antimicrobials, which are drugs used to prevent and treat infections in people, animals, and plants.
The relative safety of a medicine is quantified by the therapeutic index (TI; also known as the therapeutic ratio). The amount of a therapeutic agent that has a therapeutic impact is compared to the amount that has a harmful effect. A range of doses that optimize between efficacy and toxicity, achieving the maximum therapeutic benefit without producing intolerable side-effects or toxicity, is referred to as the therapeutic window or safety window.
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