The value that the nurse recognize as the best clinical measure of renal function is Creatinine clearance.
The amount of plasma filtered through the glomeruli in one unit of time is measured by creatinine clearance, which is a reliable indicator of glomerular filtration rate (GFR). The most accurate measurement of renal function is creatinine clearance. Both creatinine clearance and renal clearance (the capacity to excrete solutes) decrease with deteriorating renal function.
The clinical question being addressed, the level of accuracy necessary, and the discomfort to the patient all play a role in choosing the best test of renal function. A decent estimation of renal function can be obtained at the lowest possible expense and inconvenience using serum creatinine and computed creatinine clearance. If the urine collection is thorough, the urinary creatinine clearance will be more precise.
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