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The molecules on the left act as inhibitors of glycolysis and that act as activators is -

  • Glucose-6-phosphate inhibits hexokinase. ATP and citrate inhibit phosphofuctokinase.
  • ATP, acetyl-CoA, as well as alanine all inhibit pyruvate kinase.
  • AMP and fructose-2,6-bisphosphate stimulate phosphofuctokinase.
  • AMP and fructose-1,6-bisphosphate stimulate pyruvate kinase.

What is glycolysis?

Glycolysis, also known as the glycolytic pathway or the Embden-Meyerhof-Parnas pathway, is a series of ten chemical reactions that occur in most cells to break down glucose and release energy, which is then captured and retained in ATP.

Some key features regarding the glycolysis are-

  • Two substances of pyruvate (as well as pyruvic acid) & two molecules of ATP are produced by one glucose molecule (plus coenzymes & inorganic phosphate).
  • If there is enough oxygen, pyruvate enters the tricarboxylic acid cycle; otherwise, it is fermented in to the lactic acid or ethanol.
  • As a result, glycolysis generates all ATP for cellular energy needs but also building blocks for the synthesis of many other cellular products.

To know more about the glycolysis, here

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