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After binding by E. coli RNA polymerase, the correct order of events for transcription initiation is A) closed complex formation, open complex formation, promoter clearance, and start of RNA synthesis.

What are the 4 steps in transcription initiation?

Transcription is the name given to the process in which DNA is copied to make a complementary strand of RNA. RNA then undergoes translation to make proteins. The major steps of transcription are initiation, promoter clearance, elongation, and termination.

The polymerase initially binds nonspecifically to DNA and migrates along the molecule until the σ subunit binds to the -35 and -10 promoter elements, forming a closed-promoter complex.

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