The Island Hoppers Development Corporation plans to develop a new dining, shopping, and luxury hotel complex within a special management area near Waikiki. It will likely be required to------SMA major permits are for projects with a substantial adverse impact on the area's environment or ecology or that will contribute significantly to the cumulative impact of area development. SMA minor permits are for projects valued at less than $500,000.
Spinal muscular atrophy (SMA) :
is a genetic condition that makes the muscles weaker and causes problems with movement. It's a serious condition that gets worse over time, but there are treatments to help manage the symptoms.
How does a person get SMA?
Most kinds of SMA are caused by a problem with a gene called the SMN1 gene. The gene does not make enough of a protein needed for the motor neurons to work normally. The motor neurons break down and can't send signals to the muscles. A child with SMA gets one copy of the SMN1 gene from each parent.
Learn more about cumulative impact:
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