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A bone marrow biopsy is a painful procedure in which marrow is removed from bone and examined. A doctor who performs a bone marrow biopsy most likely wants to observe which of these?

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Is a bone marrow biopsy painful? Most people need only local anesthesia, as bone marrow aspiration, in particular, can cause brief, but sharp, pain. Individuals are fully awake during the procedure, but the aspiration and biopsy site will be numbed to reduce pain.

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