This pedigree shows the inheritance Leber congenital amaurosis (LCA) which is a type of hereditary blindness. Individuals with this disease lose their vision during childhood. 3. What is the inheritance pattern shown?

Autosomal recessive inheritance characterizes by the expression of the recessive trait. Two copies of these alleles are needed to express the recessive phenotype and no dominant alleles.

Let us assume that the diallelic autosomal gene has a dominant allele L that expresses the normal phenotype and the recessive allele l that expresses the altered phenotype. The pedigree would be as shown in the attached files.

To interpret the pedigree, remember that

Squares represent males
Circles represent females
Empty figures express normal/healthy/not affected individuals
Solid black figures represent affected individuals

shivjimishraVT shivjimishraVT · Answer 2 · 2022-03-11T10:20:15+01:00

Leber congenital amaurosis (LCA) is a type of Autosomal recessive inheritance. Individual with this disease loses their vision during childhood.

What is Pedigree Analysis?

The study of the inheritance of genetic traits in several generations of a human family in the form of a family tree diagram is called Pedigree analysis.

Two copies of these alleles are required to express the recessive phenotype and are responsible for the inheritance of LCA. As autosomal recessive inheritance expresses its trait when both the alleles of each parent are in recessive form and the resulted offspring shows the inheritance pattern.

Hence, LCA is an autosomal recessive inheritance caused by the expression of both recessive alleles simultaneously in an individual.

To learn more about Autosomal recessive inheritance, refer to the link:

https://brainly.com/question/26332629