Answer:
consumption of large amount of alcohol misuse leads to organs damaged include the brain and nervous system, heart, liver and pancreas too by increases in oxidative stress, modifications of proteins, dysregulation in lipid metabolism, methylation impairments and signal transduction pathways which affect cell function and survival.
alcohol can make voice raspy and can affect singing voice. it damages and irritate a larynx leading to swollen and inflamed vocal cords.
Consumption of large concentration of alcohol shifts the membrane transition temperature to lower values, and disturb phospholipid acyl chains in the gel phase.
In cell membrane alcohol molecules damage the outer cell membrane and penetrate the cytoplasm and destroy the cytoplasm protein and inner structure of the cell molecules.
Explanation: